Awesome, that you took the time to look into this, it’s been on my mind since the meetup as well! 
I think we can rely on it for 99% of packages. Most libraries don’t ship AOT compiled byte code but Clojure source code. For libraries (minority I assume) that don’t do this we could establish some ways they can work
around this issue.
Boot could be a useful companion in this adventure. It provides a convenient utility called Pods in which we can load dependencies in an isolated manner. If we need a fresh environment we just use a fresh pod. We can also dynamically add files from jars to some directory that we create beforehand.
I think it is highly preferable to use jars as foundation for this kind of effort since not everyone may be properly tagging releases on Github or even link to their Github repo in their pom.xml.
Having raw data is an amazing idea for editor integration and many other things. I’d expect something like this also to be a welcome addition to codox if it isn’t already present.
I’m in a bit of a rush right now but would love to collaborate on this kind of effort. I’ll try to whip up a basic example of using pods and copying jar files into some directory tomorrow or so.