You could probably set this up with inotify and marginalia - so that each time you save your file it would regenerate the HTML and then it’d autorefresh in your browser window?
I’ve found running marginalia slow, so you’d need to find a way to speed things up by maybe having it run as some daemon
I do really like it’s side-by-side layout though and I use it in shorter programs where orgmode is overkill. And I do feel the layout is better than the traditional literate/org-mode vertical layout.
That all being said - I’ve never used live-preview while writing literate programs. I find that with the right highlighting it’s basically just as nice to stick to the raw text-form. Some emacs themes seem to extend org-mode’s highlighting so that it’s all visually easier to parse
So I feel the most pragmatic solution would just be a syntax highlighting layer on top of the existing Clojure one that would highlight the comment areas appropriately (which would be still written in a markdown/marginalia style). Something so it’s not all just light grey, but similar to the way text is highlighted in org, and then visually separate the code section with like a separate background or something to that effect. I think that’d get you 80% to where you want.
But the way things are right now, it’s a bit of an eyesore writing big grey code comment blocks 