I think the necessary tools are evolving. There’s been fantastic work like https://github.com/MastodonC/kixi.stats and others to develop our own Clojure libraries and as Data Science becomes more and more mainstream, there will be more and more efforts to develop them for the JVM and we, as Clojurists, can leverage that.
Graal is a really intriguing direction but is still a ways off. But again, the JVM lets us take advantage of any advances there too.
The pragmatic aspect of Clojure is very nice.