Awesome, that you have the chance to use Clojure again 
If you don’t need to build any super interactive UI (a visual editor or similar), then I would go with htmx, Hiccup, next-jdbc for SQLite, Ring, httpkit and TailwindCSS. This video should provide a good overview regarding htmx + Hiccup:
Htmx will help to avoid a lot of API churn and security issues down the road:
