VSCode is much friendlier to beginners, uses a UX language that is more modern with more modern shortcuts, and it plays well with Windows.
If you’re someone who generally prefers say MacOS or Windows over Linux. You’ll probably be happier with CSCode and Calva.
Emacs is way more customizable and extensible, and has many features other editors lack. It excels at a keyboard only workflow (no need to use the mouse for anything). You can even easily add your own custom features to it. It’s feature set for Clojure editing is probably unmatched, but I’d say Calva is 90% there, and you probably won’t miss the difference. It can also be run from the command line fully without a UI if that’s something you care about.
If you’re someone who likes to thinker and customize everything. If you like to do things without a mouse. And if in general you prefer Linux over MacOS or Windows, you’ll probably like Emacs + Cider better.
Edit: Just wanted to add, Calva and Cider both use The Orchard as their underlying “backend”. The difference is mainly in their editor integration.