The project bb-web shows that it is possible to code a SPA web app in Clojure without having to install Java/Clojurescript. The heavy load is carried by Babashka and its Small Clojure Interpreter (SCI).
bb-web makes use of a preliminary Babashka release with http-kit included, which gives a very lightweight back-end compared to the JVM. Using SCI in the front-end significantely improves the error messages compared to self hosted Clojurescript.
The only project-immanent ingredient is a 50 loc Clojurescript file (precompiled to 1MB) which makes Reagent and cljs-ajax availabe to SCI.
On can readily start changing the example. It is delibarately taken from the guestbook-reagent code of the Luminus book, itself being a main go-to place for learning how to develop web-apps in Clojure. bb-web is meant to lower the bar even further to enter that road. The project description is especially directed towards MS-Windows™ users.